The Role of 8-Amidoquinoline Derivatives as Fluorescent Probes for Zinc Ion Determination

Mass-spectrometry-based and X-ray fluorescence-based techniques have allowed the study of distribution Zn2+ ions at extracellular intracellular levels over past few years. However, there are some issues during purification steps, sample preparation, suitability for quantification, instruments’ availability. Therefore, work on fluorescent sensors based 8-aminoquinoline as tools to detect in environmental biological applications has been popular. Introducing various carboxamide groups into an molecule create 8-amidoquinoline derivatives improve water solubility cell membrane permeability is also a recent trend. This review aims present general overview fluorophore its receptors zinc sensor probes. Various chemosensor designs their effectiveness potential recognition probe analysis were discussed. Based this review, it can be concluded that vast functional primarily because fast reactivity, good selectivity, bio-compatibility, especially applications. To better understand ion fluorophores’ function, diversity coordination complex geometries need further studies. provides information elucidating, designing, exploring new future studies improvement chemosensors selective sensitive Zn2+.